What is Metolazone used for: Side effects and Precautions?

Why is this medication prescribed?

To reduce the swelling and fluid retention such as congestive heart failure or kidney disease metolazone is used, it is a water pill that works by increasing the amount of urine you make by reducing the amount of water and salt in your body. Metolazone is a kind of drug that is used in the treatment of high blood pressure. By decreasing blood pressure it helps us to prevent strokes, heart attacks, and kidney problems. Metolazone also helps to decrease the risk of trouble breathing.

How should this medicine be used? 

Metolazone is available in the form of tablets to take by mouth. Usually, the doctor prescribed this medication to take once a day. Remember to use this medication regularly at the same time each day. Don’t try to use this medication more or less often than prescribed by your health care professionals and use the metolazone exactly in the same quantity that your doctor prescribed you to take. If you have any type of question or anything that you don’t understand then ask that to your health care professionals and follow your prescription label carefully as directed.

The dosage of this medication totally depends upon your medical condition and response to treatment but first, your doctor starts your dosage by a very low amount. After that he/she will increase your dosage by watching medical conditions and response to treatment or this medication. And remember that it is not a cure, it only controls high blood pressure. It will take 3 to 6 weeks to see a lowering or controlling of your high blood pressure. So, don’t stop using metolazone even if you feel well. Don’t try to stop using this medication without talking to your health care professionals.

During your treatment with this medication, your symptoms should be expected to improve, if your symptoms do not improve after using this medication and getting worse or during your treatment with metolazone then talk to your doctor or pharmacist. Read all the instructions very carefully that are provided by your health care professionals.

If you want to get the most benefits from the metolazone then use this medication regularly in order. And always use it at the same time each day. Until consulting your health care professional won’t try to stop using this medication.  

Other uses of metolazone

Ask your health care professional for more information because metolazone is also prescribed for other uses.

What special dietary instructions should I follow?

Always follow your dietary recommendations and exercise plan made by your health care professional. And ask your doctor for instructions about any restrictions on food, beverages, or activity. Or if your doctor didn’t give you any instructions, you can continue your normal diet. 

What special precautions should I follow?

You should have followed this special precaution before using metolazone:

  • If you are allergic to metolazone, sulfa drugs, thiazides, any other medications, or any of the ingredients in metolazone tablets then tell your doctor and pharmacist and ask them for all ingredients.
  • Your doctor will not prescribe you this medication, if you have kidney or liver failure, tell your doctor and pharmacist.
  • If you have or have ever had diabetes, systemic lupus erythematosus, heart, gut out, kidney, or liver disease then tell your doctor and pharmacist.
  • If you are having surgery, including dental surgery while you are using metolazone then tell your doctor and dentist.
  • Don’t ever try to drive a car because this drug may make you dizzy or drowsy or not operate any machinery until you know how this medication affects you.
  • If you are taking some prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products especially warfarin, aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs), furosemide, insulin, other medications for diabetes and high blood pressure, medications for asthma, colds, pain, seizures, methenamine, sedatives, oral steroids, tranquilizers, and vitamin D, or planning to take them while using this product then tell your doctor and pharmacist.
  • If you are pregnant, breastfeeding, or plan to become pregnant while using metolazone. If you become pregnant while using it then tell your doctor and pharmacist.
  • If you are an alcoholic person then tell your doctor about this before starting to use this medication and ask them about the safe use of alcoholic beverages because alcohol can make the side effects worse.
  • While using metolazone, it can make your skin sensitive to sunlight. So, try to avoid going outside unnecessarily to sunlight and to wear protective clothing, sunglasses, and use sunscreen.
  • If you start taking the treatment with this medication you should know about the common problem you’ll face that when you try to get up too quickly from a lying position you’ll feel dizziness, lightheadedness, and fainting. So, if you want to avoid this problem then stand up from bed slowly, and for a few minutes, before standing up, rest your feet on the floor.

If you have experienced or faced any of the problems mentioned above then contact your health care professionals immediately. Follow all the mentioned precautions carefully, these are all precautions that you can take while using this product.

What side effects can metolazone cause?

Don’t use this medication without your doctor’s prescription, Doctors will suggest metolazone by judging the benefit to you is greater than the risk of side effects. You should have to know the side effects and symptoms of this medication before taking this.

Some common side effects of metolazone:

If you experience any of these common side effects or symptoms and do not go away  or are getting worse, then stop taking or using metolazone and call your doctor immediately:

  • You’ll feel restlessness.
  • You’ll feel a decrease in vision or eye pain.
  • You’ll feel nausea or vomiting,
  • You’ll feel faint.
  • You’ll feel seizures.
  • You’ll feel constipation.
  • You’ll feel diarrhea.
  • You’ll feel joint pain or swelling.
  • You’ll feel dizziness.
  • You’ll feel weakness.
  • You’ll feel a headache.
  • You’ll feel muscle cramps.

Some serious side effects of metolazone:

If you experience any of these serious side effects or symptoms and do not go away  or are getting worse, then stop taking or using metolazone and call your doctor immediately:

  • You’ll feel hives.
  • You’ll feel swelling of the lips, eyes, hands, feet, ankles, or lower legs.
  • You’ll feel hoarseness.
  • You’ll feel extreme tiredness.
  • You’ll feel the loss of appetite.
  • You’ll feel rash, itching, or swelling especially on the face, tongue, or throat.
  • You’ll feel blistering or peeling skin.
  • You’ll feel pain in the upper right part of the stomach.
  • You’ll feel the yellowing of the skin or eyes.
  • You’ll feel flu-like symptoms.
  • You’ll feel dry mouth, dark urine, decreased sweating, dry skin, and other signs of dehydration.
  • You’ll feel chest pain.
  • You’ll feel fast, irregular, or pounding heartbeats.
  • You’ll feel difficulty swallowing or breathing.
  • You’ll feel a sore throat with fever.
  • You’ll feel unusual bleeding or bruising.
  • You’ll feel an upset stomach.

It can also cause other side effects and if you have any unusual problems while using this product then immediately contact your health care professionals because this is not the complete list of all symptoms and side effects of this medication.

What can I do if I forget a dose?

If you forgot to take this medication and if it is near the time of your next dose then we suggest you please skip that dose and take it at the next dose at the regular time. Don’t take the dose at irregular times. It makes your dose double and it would be harmful to you.

What happens if I overdose?

Some of the symptoms or side effects can occur because of an overdose of this medication. Talk to your healthcare professionals if you have experienced any of the following symptoms or side effects immediately. 

Some symptoms of overdose:

  • You’ll feel slow or difficult breathing.
  • You’ll feel an upset stomach.
  • You’ll feel a coma.
  • You’ll feel dizziness.
  • You’ll feel drowsiness.
  • You’ll feel faint.

What are the Interactions of metolazone with other drugs?

Your healthcare professionals can already be aware of any drug interactions. Don’t try to change, stop, or start the dosage of any medicine before checking or before talking to your doctor or pharmacist. If you are taking some prescription and nonprescription medications, other vitamins, nutritional supplements, herbal products, including prescription drugs, nonprescription drugs, or planning to take them, then tell your doctor and pharmacist before starting the treatment with this product.

Some drugs can interact with metolazone:

  • Cholestyramine,
  • Cisapride,
  • Colestipol,
  • Diazoxide,
  • Digoxin,
  • Dofetilide,
  • Lithium.

Before using the metolazone medication, tell your healthcare professionals of all the products you use because this documentation doesn’t contain all the possible interactions. And the most important thing when you are taking these products doesn’t start, stop, or change the dosage of any medicines you are using without your doctor’s approval. 

What can I know about the storage and disposal of this medication?

You should have disposed of all the medication that is unneeded in a special way to ensure that children, pets, and other people can’t consume them. You can not flush them or pour them into the drain. You can return them to the pharmacist or the best way is that you can take back the program for returning your medicines.

Store this medication at room temperature and keep them away from light or excessive heat and moisture. And put them away from the reach of the pets and children, we suggest you put that medicine in a tightly closed container in which they came. 

What other information should I know?

Don’t miss any of your doctor and laboratory appointments because your doctor will check the response of this medicine then he/she will tell you the update or other pieces of information. So, keep all your appointments with your doctor, pharmacist, the laboratory. And before having any laboratory test, if you are already taking this product then tell your doctor and the laboratory personnel. 

Talk to your healthcare professionals if you feel your health condition is getting worse or your dose may need to be adjusted. And remember don’t try to switch the brand name of the medicine you are taking without talking to your healthcare professionals because as different brands of metolazone it would work differently in the body.

And ensure that no one is taking your medicine or no one has them. It is very important to tell your pharmacist about all your prescriptions and non-prescription you were taking and make a list of them and carry the list all the time. It would help you in case of emergencies. When you meet or visit your doctor you should bring the list. It’s important to your doctor.

Brand names

  • Mykrox
  • Zaroxolyn

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