What are Triptorelin uses, side effects & precautions?

Why did doctors prescribe triptorelin injections?

Triptorelin injection belongs to a class of drugs called gonadotropin-releasing hormone (GnRH) agonists. It is used in the treatment of advanced prostate cancer and endometriosis. Prostate cancer needs the male hormone testosterone to grow and spread them fastly in the body. So, triptorelin injection works by reducing the amount of testosterone that the body makes. Because of this the growth of cancer has slowed or stopped for some time and helps relieve symptoms such as painful/difficult urination. It is not the cure of cancer. It also reduces the number of certain hormones in the body.

How to use triptorelin injection?

Triptorelin injection is available in the form of an extended-release suspension and by a nurse or a doctor in a clinic or medical office, it is injected into the muscle of either buttock. There are mainly four types of dosages that your healthcare professionals will prescribe you when you use this injection for the treatment of prostate cancer.

What are the dosages of triptorelin?

Usually, your healthcare professionals will prescribe you:-

  • 3.75 mg of triptorelin injected into your body every 4 weeks  
  • 11.25 mg of triptorelin injected into your body every 12 weeks 
  • 22.5 mg of triptorelin (Trelstar) injected into your body every 24 weeks
  • 22.5 mg of triptorelin (Triptodur) injected into your body every 24 weeks when you used this injection on children with central precocious puberty

In the first few weeks after getting an injection of triptorelin medication, it can cause an increase in certain hormones. So, during the treatment time period, your doctor will monitor you carefully for any new or worsening symptoms. Ensure that all the directions have been followed exactly on your prescription label carefully. The injection prescribed by your doctors can not be used more or less. The dosage of this injection depends on your medical condition or your response to treatment. And always mark your calendar to keep track of your next dose to remember using this medication. 

Until your full prescribed amount is finished, do not stop using this medication even if you feel well or your symptoms disappear. And if you feel your condition doesn’t improve then you may contact your healthcare professionals. Your testosterone level will increase before it decreases during the first weeks of your treatment then contact your doctor. Your healthcare professionals will tell you when you have stopped using this medication. If you don’t understand any of the parts then ask your healthcare provider to explain all the things again.

What is triptorelin injection side effects?

Without your healthcare professionals don’t try to use triptorelin injection because they will suggest this medication only by judging the most benefit to you is greater than the risk of side effects. Because triptorelin injection is a medication that can be used only by people who have some serious side effects. And never try to use it for a longer time period than prescribed. 

When you are using triptorelin injection and if you have seen any of these side effects or symptoms mentioned below then contact your healthcare professionals immediately.

Some common triptorelin injection side effects:

  • You’ll feel hot flashes, sweating, or clamminess.
  • You’ll feel decreased sexual ability or desire.
  • You’ll feel mood changes such as crying, anger, aggression, irritability, and impatience.
  • You’ll feel pain, itching, swelling, or redness at the place where the injection was given.
  • You’ll feel difficulty falling asleep or staying asleep.
  • You’ll feel leg or joint pain.
  • You’ll feel a headache.
  • You’ll feel heartburn.
  • You’ll feel constipation.
  • You’ll feel breast pain.
  • You’ll feel depressed.
  • You’ll feel a cough.
  • You’ll feel nausea.
  • You’ll feel vomiting.
  • You’ll feel diarrhea.
  • You’ll feel an upset stomach.
  • You’ll feel vaginal bleeding.
  • You’ll feel cold or flu symptoms.

Some serious triptorelin injection side effects:

  • You’ll feel hoarse.
  • You’ll feel seizures.
  • You’ll feel chest pain.
  • You’ll feel pain in the neck, arms, jaw, or back.
  • You’ll feel slow or difficult speech.
  • You’ll feel dizzy or faint.
  • You’ll feel pain spreading to your jaw or shoulder.
  • You’ll feel weakness or numbness of an arm or leg.
  • You’ll feel the breath that smells fruity.
  • You’ll feel decreased consciousness.
  • You’ll feel high blood sugar.
  • You’ll feel hunger, a fruity breath odor.
  • You’ll feel hives.
  • You’ll feel rash.
  • You’ll feel itchy.
  • You’ll feel difficulty breathing or swallowing.
  • You’ll feel swelling of the mouth, throat, face, eyes, tongue, or lips.
  • You’ll feel the loss of bladder or bowel control.
  • You’ll feel nerve problems, back pain, problems with balance or coordination, or tingling in your legs or feet.
  • You’ll feel not be able to move your legs.
  • You’ll feel bone pain.
  • You’ll feel painful or difficult urination.
  • You’ll feel the blood in the urine.
  • You’ll feel frequent urination.
  • You’ll feel extreme thirst.
  • You’ll feel muscle weakness.
  • You’ll feel blurred vision.
  • You’ll feel a dry mouth.

What are other uses of triptorelin?

And if you want to know some other uses of this medication in detail then contact your healthcare professional and you can ask them for more information or other uses of triptorelin infection.

What special precautions could I take?

You should have followed all these special precautions carefully while using the triptorelin injection:

  • If you are allergic to triptorelin, any other drugs, or similar drugs such as leuprolide (Lupron, Viadur, Eligard) or goserelin (Zoladex) then tell your doctor and pharmacist and ask them for all ingredients of triptorelin injection by which you are allergic.
  • If you have ever had a heart attack or stroke, heart disease, long QT syndrome or other heart rhythm disorder, diabetes, mental illness, epilepsy, other seizure disorder, an electrolyte imbalance, or a tumor or blood vessel problem in your brain then tell your doctor and pharmacist before having triptorelin injection.
  • This can be very harmful to your infant because when you breastfeed it can pass into breast milk. So you can not breastfeed while using the triptorelin injection.
  • This injection can affect fertility in men (ability to have children). Talk to your doctor and pharmacist before having a triptorelin injection.
  • If you are taking any vitamins, nutritional supplements, prescription or non-prescription medication or drugs, any other drug or medicine, herbal products, or planning to take them while using this injection then tell your doctor and pharmacist.
  • If you become pregnant or plan to become pregnant while you are using this triptorelin injection then tell your doctor and pharmacist immediately. 

What do I do if I forget a dose?

You can make your dose double if you take the dose at irregular times. If in case, the time is near your next dose and you forget to take your last dose of this medication then we suggest you please skip that dose and take it at the next dose at the regular time.

What other information should I know?

At the time of meeting your healthcare professionals, don’t forget to carry the laboratory report. And the most important thing is to never miss your doctor and laboratory appointments because your healthcare professionals will check the response of this medicine then he/she will tell you the update or other pieces of information. So, keep all your appointments with your doctor, pharmacist, and the laboratory. And before having any laboratory test, if you are already taking this product then tell your doctor and the laboratory personnel. Talk to your healthcare professionals if you feel your health condition is getting worse or your dose may need to be adjusted.

If you are taking any prescription and non-prescription medication or drugs, while you are using this medication, it is very important to tell your healthcare professionals about this. To make it easy and unforgettable, you can create a list of all prescription and non-prescription medications or drugs and any other drug or medicine you are taking. You can show that list to your healthcare professionals or pharmacists at the time of visit or meeting them. It would help you in case of emergencies. It would help you in case of emergencies.


Hope you find this article very useful. Please tell us your experience with this article in the comment section and keep visiting for further pieces of information.

Leave a Comment

Your email address will not be published. Required fields are marked *