What is Sulindac medication uses, side effect & precautions?

Why is this medication prescribed?

Sulindac is used in the treatment to reduce pain, tenderness, swelling, stiffness, rheumatoid arthritis, ankylosing spondylitis, gouty arthritis, and shoulder bursitis/tendonitis. Sulindac comes under the class of medications called NSAIDs (Nonsteroidal anti-inflammatory drugs). It stops making a natural substance in your body that causes pain, fever, and inflammation. In 1969, sulindac was patented and in 1976, was approved for medical use and it sold under the brand name Clinoril.

The shoulder pain is caused by tendinitis that is an aggravation of the tissue that associates muscle to bone and bursitis, which is inflammation of a fluid-filled sac in the shoulder joint, can also be treated by this medication. Before taking this drug for medication chronic conditions such as arthritis then ask your healthcare professionals first about the non-drug treatments and/or using other medications to treat your pain. 

How should this medicine be used?

Sulindac available in the form of a tablet to take by mouth. Usually, doctors will prescribe this medication to take with food, right after meals, or with antacids to prevent stomach upset twice a day. After taking this drug, don’t try to lie down for at least 10 minutes. Don’t try to use this medication more or less often than prescribed by your health care professionals and use the sulindac exactly in the same quantity that your doctor prescribed you to take. Remember to use this medication regularly at the same time each day. 

If you take this medication more than 400 milligrams per day then it can increase your risk of liver problems. If you have any type of question or anything that you don’t understand then ask that to your health care professionals and follow your prescription label carefully as directed. When you are taking sulindac, it only helps in the control of the pain, it doesn’t cure arthritis. Before you feel the benefit of sulindac, it can take 1 or 2 weeks to give you the full benefit.

If you want to get the most benefits from the sulindac then use this medication regularly in order. And always use it at the same time each day. Until consulting your health care professional won’t try to stop using this medication. If you are using this medication and you are feeling well then continue to use sulindac don’t try to stop using it without consulting your health care professional.

Other uses for sulindac

Your health care professional also prescribed sulindac for other uses such as to reduce the number of abnormal growths in the large intestine and a condition in which thousands of polyps form in the large intestine and cancer may develop that is also known as the rectum in patients with familial adenomatous polyposis. To treat the cancer use Hydroxyurea medicine. Ask your health care professional for more information or other uses of this medication.

What happens if I overdose?

Some of the symptoms or side effects can occur because of an overdose of this medication. Talk to your healthcare professionals if you have experienced any of the following symptoms or side effects immediately. 

Some symptoms of overdose:

  • You’ll feel dizziness.
  • You’ll feel decreased urination.
  • You’ll feel blurred vision.
  • You’ll feel the loss of consciousness.
  • You’ll feel faint.
  • You’ll feel an upset stomach.

What special dietary instructions should I follow?

Always follow your dietary recommendations and exercise plan made by your health care professional. And ask your doctor for instructions about any restrictions on food, beverages, or activity. Or if your doctor didn’t give you any instructions, you can continue your normal diet.

What special precautions should I follow?

You should have followed this special precaution before using sulindac:

  • If you are allergic to sulindac, aspirin, or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), or any other medications then tell your doctor and pharmacist and ask them for all ingredients.
  • If you have or have ever had any of the conditions asthma, especially if you also have frequent stuffy or runny nose or nasal polyps, heart failure, kidney stones, swelling of the hands, arms, feet, ankles, or lower legs, or liver or kidney disease then tell your doctor and pharmacist.
  • If you are pregnant, breastfeeding, or plan to become pregnant while using sulindac. If you become pregnant while using it then tell your doctor and pharmacist.
  • During pregnancy, if you are taking it around 20 weeks or later. It causes problems with delivery and can harm the fetus and.
  • While taking sulindac, don’t take sulindac if you become pregnant or after 20 weeks of pregnancy, unless told by your doctor.
  • If you are taking some prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products especially any other product and vitamin D, or planning to take them while using sulindac then tell your doctor and pharmacist.
  • If you are having surgery, including dental surgery then tell your doctor and dentist.
  • Don’t try to take this medication for a longer period or at a higher dose if you are 75 years of age or older and ask about the risks and benefits of taking sulindac to your doctor or pharmacists.

If you have experienced or faced any of the problems mentioned above then contact your health care professionals immediately. Follow all the mentioned precautions carefully, these are all precautions that you can take while using this product.

What are the side effects of sulindac?

Don’t use this medication without your doctor’s prescription, Doctors will suggest sulindac by judging the benefit to you is greater than the risk of side effects. You should have to know the side effects and symptoms of this medication before taking this.

Some common side effects of sulindac:

If you experience any of these common side effects or symptoms and do not go away  or are getting worse, then stop taking or using sulindac and call your doctor immediately:

  • You’ll feel diarrhea.
  • You’ll feel constipation.
  • You’ll feel a headache.
  • You’ll feel gas.
  • You’ll feel ringing in the ears.
  • You’ll feel dizziness.
  • You’ll feel an upset stomach.
  • You’ll feel nervous.
  • You’ll feel nausea.
  • You’ll feel vomiting.
  • Can raise your blood pressure.

Some serious side effects of sulindac:

If you experience any of these serious side effects or symptoms and do not go away  or are getting worse, then stop taking or using sulindac and call your doctor immediately:

  • You’ll feel fever.
  • You’ll feel chills.
  • You’ll feel a cough.
  • You’ll feel chest pain.
  • You’ll feel blisters.
  • You’ll feel rash, itching, swelling especially on the face, tongue, or throat.
  • You’ll feel unexplained weight gain.
  • You’ll feel shortness of breath or difficulty breathing.
  • You’ll feel swelling of the abdomen, feet, ankles, or lower legs.
  • You’ll feel sweating.
  • You’ll feel flushing.
  • You’ll feel muscle or joint pain.
  • You’ll feel hives.
  • You’ll feel swelling of the eyes, face, lips, tongue, throat, arms, or hands.
  • You’ll feel difficulty swallowing.
  • You’ll feel hoarseness.
  • You’ll feel pale skin.
  • You’ll feel a fast heartbeat.
  • You’ll feel excessive tiredness.
  • You’ll feel the yellowing of the skin or eyes.
  • You’ll feel cloudy, discolored, or bloody urine.
  • You’ll feel back pain.
  • You’ll feel difficult or painful urination.
  • You’ll feel blurred vision or other problems with sight.
  • You’ll feel unusual bleeding or bruising.
  • You’ll feel a lack of energy.
  • You’ll feel the loss of appetite.
  • You’ll feel pain in the upper right part of the stomach.
  • You’ll feel flu-like symptoms.
  • You’ll feel unexplained stiff neck

It can also cause other side effects and if you have any unusual problems while using this product then immediately contact your health care professionals because this is not the complete list of all symptoms and side effects of this medication.

What can I do if I forget a dose?

If you forgot to take this medication and if it is near the time of your next dose then we suggest you please skip that dose and take it at the next dose at the regular time. Don’t take the dose at irregular times. It makes your dose double.

What are the Interactions of sulindac?

Your healthcare professionals can already be aware of any drug interactions. Don’t try to change, stop, or start the dosage of any medicine before checking or before talking to your doctor or pharmacist. If you are taking some prescription and nonprescription medications, other vitamins, nutritional supplements, herbal products, including prescription drugs, nonprescription drugs, or planning to take them, then tell your doctor and pharmacist before starting the treatment with this product.

Some drugs can interact with this:

  • Aliskiren or ACE inhibitors such as captopril, lisinopril
  • Angiotensin II receptor blockers such as losartan, valsartan
  • Cidofovir or dimethyl sulfoxide such as DMSO
  • Lithium, methotrexate, or corticosteroids such as prednisone
  • Water pills such as diuretics, furosemide
  • Anti-platelet drugs such as clopidogrel
  • Blood thinners such as dabigatran/enoxaparin/warfarin

If you are using some other drugs also at the time when you are using this product it can increase the risk of bleeding. Before using the sulindac, tell your healthcare professionals of all the products you use because this documentation doesn’t contain all the possible interactions. And the most important thing when you are taking these products doesn’t start, stop, or change the dosage of any medicines you are using without your doctor’s approval. 

What can I know about the storage and disposal of this medication?

You should have disposed of all the medication that is unneeded in a special way to ensure that children, pets, and other people can’t consume them. You can not flush them or pour them into the drain. You can return them to the pharmacist or the best way is that you can take back the program for returning your medicines.

Store this medication at room temperature and keep them away from light or excessive heat and moisture. And put them away from the reach of the pets and children, we suggest you put that medicine in a tightly closed container in which they came. 

What other information should I know?

Don’t miss any of your doctor and laboratory appointments because your doctor will check the response of this medicine then he/she will tell you the update or other pieces of information. So, keep all your appointments with your doctor, pharmacist, the laboratory. And before having any laboratory test, if you are already taking this product then tell your doctor and the laboratory personnel. Talk to your healthcare professionals if you feel your health condition is getting worse or your dose may need to be adjusted. 

And ensure that no one is taking your medicine or no one has them. It is very important to tell your pharmacist about all your prescriptions and non-prescription you were taking and make a list of them and carry the list all the time. It would help you in case of emergencies. When you meet or visit your doctor you should bring the list. It’s important to your doctor.


Hope you find this blog useful. Please tell us your experience with this blog in the comment section and keep visiting for further pieces of information.

Leave a Comment

Your email address will not be published. Required fields are marked *