What is Cisapride medicine uses, side effects & precautions?

Why is this medication prescribed?

Cisapride is sold under the brand name Propulsid, and it is used in the treatment of gastric reflux, which is usually experienced as heartburn. Some people have nighttime heartburn symptoms. For treatment of this symptom, cisapride is used for those who have not responded to other treatments. Cisapride helps in increasing the digestion rate at which your esophagus, stomach, and intestines move. It also helps to increase the strength of your lower esophageal sphincter at which your stomach empties into your intestines.

Cisapride is not used by the people who are allergic to it, or if you have bleeding or an obstruction in your stomach, heart disease or hardening of the arteries, a heart rhythm disorder. Always before taking this medication talk to your doctor or pharmacists.

Cisapride can also be used for some other purposes that are not mentioned in this document or in this medication guide.

Some important warning of Cisapride 

In the United State, Cisapride is only available for the persons who are signed up by their doctors.  Whether you are taking cisapride or not, always talk to your doctor or pharmacist first about this medication.

If in history you have ever had heart problems. irregular heartbeats, heart disease, severe dehydration, vomiting, eating disorders, or kidney or lung failure then talk to your doctor or pharmacists first because it can lead to death. Cisapride may cause some other serious irregular symptoms.

Remember that if you taking any of the medications mentioned below then don’t try to take cisapride or don’t drink the grapefruit juice if you are taking this medication:

Promethazine, Crixivan, ritonavir (Norvir), Bepridil, chlorpromazine, clarithromycin, erythromycin (E.E.S., E-Mycin, Ery-Tab), fluconazole, amiodarone, disopyramide, quinidine, procainamide, sotalol, fluphenazine, itraconazole, ketoconazole, amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, maprotiline, nefazodone, nortriptyline, protriptyline, trimipramine, mesoridazine, perphenazine, prochlorperazine, sertindole, sparfloxacin, thioridazine, thiothixene, trifluoperazine, or troleandomycin (Tao).

Try to always keep all appointments with your healthcare professionals and the laboratory. Your healthcare professionals will check your body’s response towards this medication through some lab tests and don’t ever try to take less or more of cisapride than prescribed by your healthcare professionals. If you experience any of the following symptoms mentioned above or any other then call your doctor or pharmacists immediately.

How should Cisapride be used?

Cisapride is available in both forms tablets or liquid to take by mouth. Usually, doctors will prescribe this medication taken four times a day, at bedtime or 15 minutes before meals. If any part that you do not understand ask your doctor or pharmacist to explain. Always follow the directions exactly on your prescription label carefully. Don’t ever try to take less or more of cisapride than prescribed by your healthcare professionals.

Before taking the liquid form of this medication, shake the bottle well and then measure the dose with a special dose-measuring spoon or medicine cup, do not measure the dosage with a regular tablespoon.

Other uses of Cisapride medicine

Ask your doctor or pharmacist for more information about the prescribed treatments for other diseases of cisapride medication because cisapride should not be prescribed for other uses.

What special dietary plans should I follow?

Don’t drink alcohol, or Grapefruit juice, and don’t eat grapefruit. Unless he/she tells you to continue your normal diet.

Cisapride side effects

Don’t use it for a longer time period than prescribed, but in case, If you’re using this medication for prolonged or repeated long periods then it may result in some serious side effects. If you notice or feel any of the new or worsening symptoms then tell your doctor or pharmacist.

This medication only uses serious side effects because people that are using cisapride medication have some serious side effects. Don’t use this medication without your doctor’s prescription, Doctors will suggest cisapride medication by judging the benefit to you is greater than the risk of side effects.

Some common side effects of Cisapride:

  • You’ll feel a stuffy nose.
  • You’ll feel constipation.
  • You’ll feel coughing.
  • You’ll feel diarrhea.
  • You’ll feel an upset stomach.
  • You’ll feel stomach discomfort.
  • You’ll feel a headache.

Some serious side effects of Cisapride:

If you are facing any of the side effects of this medication mentioned below then call your doctor or pharmacists immediately, if you experience any of the following symptoms:

  • You’ll feel vision changes.
  • You’ll feel chest pain.
  • You’ll feel fast or irregular heartbeats.
  • You’ll start feeling like you might pass out.\
  • Your urination has increased.

If you have any unusual problems apart from these while using cisapride medication then immediately contact your doctor or pharmacist because this is not the complete list of the all symptoms and side effects of cisapride.

What special precautions should I follow?

Some special precaution of cisapride medicine you should have followed before using this medication:

  • If you are allergic to cisapride or any other drugs then tell your doctor and pharmacist.
  • Always remember that don’t take alcohol while you are using this medication because it can add to the drowsiness caused by this drug.
  • Don’t ever try to drive because this drug may make you drowsy or not operate any machinery until you don’t know how this drug affects you and you.
  • If you are breastfeeding, pregnant, or planning to become pregnant. If you become pregnant while taking cisapride, other medicines such as istradefylline pills then tell your doctor and pharmacist.
  • If you have or have ever had intestinal disorders or bleeding ulcers then tell your doctor and pharmacist.
  • If you are taking some prescription and nonprescription medications, nutritional supplements, herbal products,  other vitamins, medicine especially anti anxiety medications, anticholinergics, anticoagulants, cimetidine (Tagamet), alogliptin, or planning to take while you are taking cisapride medication then tell your doctor and pharmacist.

And don’t use cisapride medication unless your doctor or pharmacist tells you to take this medication.

What should I discuss with my doctor before taking Cisapride?

If you are allergic to cisapride, or if you have the issues mentioned below then you shouldn’t take this medication and discuss with your healthcare provider:

  • If you have a structural heart defect.
  • If your heart block or other conduction disorders.
  • If you have an eating disorder, severe dehydration, or malnutrition problem.
  • If you have ever had a kidney failure problem.
  • If you have severe lung problems or advanced cancer.
  • If you are feeling bleeding or obstruction in your stomach.
  • If you have any heart disease or hardening of the arteries.
  • If you have any heart failure history.
  • If your heart rate is slow or a heart rhythm disorder.

Ask your doctor if you are pregnant, or planning to become pregnant about this medication.

What happens if I overdose?

Some of the symptoms occur because of an overdose of cisapride:

  • Nausea,
  • Vomiting
  • Rumbling noises in the stomach
  • Flatulence
  • Diarrhea
  • Urinary frequency
  • Tremors,
  • Seizures
  • Weakness

Talk to your doctor or pharmacist if you have experienced any of the following symptoms immediately. These are very harmful to you.

What should I avoid while taking cisapride?

Don’t take alcohol while you are using this medication because it can add to the drowsiness caused by this drug or it can increase certain side effects of cisapride.

Some products such as (grapefruit or grapefruit juice) may increase the amount of cisapride available in your body that can increase certain side effects of cisapride.

Cisapride interactions with other drugs

Your doctor, pharmacist, or healthcare professionals can already be aware of any drug interactions. Don’t try to change, stop, or start the dosage of any medicine before checking or before talking to your doctor or pharmacist.

If you are taking some prescription and nonprescription medications, other vitamins, nutritional supplements, herbal products, or planning to take them then tell your doctor and pharmacist before starting the treatment with this product.

Tell your doctor about these medicines if you are using them:

  • A blood thinner such as warfarin, coumadin
  • Belladonna such as donnatal
  • Hyoscyamine such as Levsin, Cystospaz, Anaspaz
  • Propantheline such as Pro-Banthine
  • Cimetidine such as Tagamet, Tagamet HB
  • Dicyclomine such as Bentyl
  • Clidinium such as Quarzan

Before using the cisapride medication, tell your doctor or pharmacist of all the products you use because this documentation doesn’t contain all the possible interactions. And the most important thing when you are taking these products and without your doctor’s approval, don’t start, stop, or change the dosage of any medicines. 

What can I do after I forget a dose?

When you start to take cisapride medication, always remember to write down all of the instructions that your doctor or pharmacist tells you when you ask a question: what should I do if I forget a dose?

The answer is if you forgot to take cisapride medication and if it is near the time of your next dose then we suggest you please skip that dose and take it at the next dose at the regular time. Don’t take the dose at irregular times. It makes your dose double and it would be harmful to you.

How could you store and dispose of this medication?

Store this medication at room temperature and keep them away from light or excessive heat and moisture. And put them away from the reach of the pets and children, we suggest you put that medicine in a tightly closed container in which they came. Ensure that the liquid form of this product doesn’t freeze.

You should have disposed of all the medication that is unneeded in a special way to ensure that children, pets, and other people can’t consume them. You can not flush them or pour them into the drain. You can return them to the pharmacist or the best way is that you can take back the program for returning your medicines.

What other information should I know?

Don’t miss any of your doctor and laboratory appointments because your doctor will check the response of this medicine then he/she will tell you the update or other pieces of information. So, keep all your appointments with your doctor, pharmacist, and the laboratory.

Talk to your doctor or pharmacist if you feel your health condition is getting worse or your dose may need to be adjusted.

It is very important to tell your pharmacist about all your prescriptions and non-prescriptions you were talking about and make a list of them and carry the list all the time . It would help you in case of emergencies. When you meet or visit your doctor you should bring the list it’s important to you doctor.

And ensure that no one is taking your medicine or no one has them. And every time when you meet your pharmacist or doctor asks them any of the questions you have about refilling your prescription.


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